Activation of signal transduction in platelets by the tyrosine phosphatase inhibitor pervanadate (vanadyl hydroperoxide).

The protein tyrosine phosphatase (PTPase) inhibitor pervanadate (vanadyl hydroperoxide) stimulated protein tyrosine phosphorylation 29-fold more than did thrombin in intact and saponin-permeabilized platelets. Increased tyrosine phosphorylation preceded, or was coincident with, a fall in PtdIns(4,5)...

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Autores principales: Pumiglia, K M, Lau, L F, Huang, C K, Burroughs, S, Feinstein, M B
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132918/
https://ncbi.nlm.nih.gov/pubmed/1530576
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