Загрузка...
Hypolipidaemic drugs are activated to acyl-CoA esters in isolated rat hepatocytes. Detection of drug activation by human liver homogenates and by human platelets.
The formation of acyl-CoA esters of the hypolipidaemic peroxisome proliferators clofibric acid, ciprofibrate and nafenopin was studied in isolated rat hepatocytes. The concentration of ciprofibroyl-CoA in the liver of ciprofibrate-treated rats was in the range of 10-30 microM. The three drugs formed...
Сохранить в:
Главные авторы: | , , , , , , |
---|---|
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
1992
|
Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1132729/ https://ncbi.nlm.nih.gov/pubmed/1599408 |
Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|