Загрузка...

Hypolipidaemic drugs are activated to acyl-CoA esters in isolated rat hepatocytes. Detection of drug activation by human liver homogenates and by human platelets.

The formation of acyl-CoA esters of the hypolipidaemic peroxisome proliferators clofibric acid, ciprofibrate and nafenopin was studied in isolated rat hepatocytes. The concentration of ciprofibroyl-CoA in the liver of ciprofibrate-treated rats was in the range of 10-30 microM. The three drugs formed...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Bronfman, M, Morales, M N, Amigo, L, Orellana, A, Nuñez, L, Cárdenas, L, Hidalgo, P C
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132729/
https://ncbi.nlm.nih.gov/pubmed/1599408
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!