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Scavenger-receptor-mediated delivery of daunomycin elicits selective toxicity towards neoplastic cells of macrophage lineage.

Transformed cells of macrophage lineage such as J774A.1, P388D1 and IC21 take up and degrade a conjugate of the antineoplastic drug, daunomycin, with maleylated BSA with high efficiency and saturation kinetics through the scavenger receptors expressed on the surface of these cells. By contrast, tran...

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Bibliographische Detailangaben
Hauptverfasser: Mukhopadhyay, A, Mukhopadhyay, B, Srivastava, R K, Basu, S K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132722/
https://ncbi.nlm.nih.gov/pubmed/1599401
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