Human placental syncytiotrophoblast expresses two pharmacologically distinguishable types of Na(+)-H+ exchangers, NHE-1 in the maternal-facing (brush border) membrane and NHE-2 in the fetal-facing (basal) membrane.

We investigated whether highly purified preparations of basal (fetal-facing) membrane isolated from normal term human placentas possess Na(+)-H+ exchanger activity. Uptake of Na+ into basal membrane vesicles was stimulated many-fold by an outwardly directed H+ gradient. This H(+)-gradient-dependent...

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Bibliografski detalji
Glavni autori: Kulanthaivel, P, Furesz, T C, Moe, A J, Smith, C H, Mahesh, V B, Leibach, F H, Ganapathy, V
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132693/
https://ncbi.nlm.nih.gov/pubmed/1318024
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