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The structural basis of the inhibition of human alpha-mannosidases by azafuranose analogues of mannose.

Eight pyrrolidine, five pyrrolizidine and one indolizidine analogue(s) of the known alpha-mannosidase inhibitor, the azafuranose, 1,4-dideoxy-1,4-imino-D-mannitol (DIM), have been tested for inhibition of the multiple forms of alpha-mannosidase in human liver in vitro. Substitution of the ring nitro...

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Detalhes bibliográficos
Main Authors: Winchester, B, al Daher, S, Carpenter, N C, Cenci di Bello, I, Choi, S S, Fairbanks, A J, Fleet, G W
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132343/
https://ncbi.nlm.nih.gov/pubmed/8457203
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