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Multiple regulation of ornithine decarboxylase in enzyme-overproducing cells.

We have isolated from mouse FM3A cells a variant cell line, termed EXOD-1, that overproduces ornithine decarboxylase (ODC). The cells were resistant to alpha-difluoromethylornithine, an irreversible inhibitor of the enzyme, and produced the enzyme protein to the extent of approx. 3-6% of total cytos...

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Détails bibliographiques
Auteurs principaux: Kameji, T, Hayashi, S, Hoshino, K, Kakinuma, Y, Igarashi, K
Format: Artigo
Langue:Inglês
Publié: 1993
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132208/
https://ncbi.nlm.nih.gov/pubmed/8424799
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