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Effects of CoA and acyl-CoAs on GTP-dependent Ca2+ release and vesicle fusion in rat liver microsomal vesicles.

(1) CoA (IC50 23 microM) and acyl-CoAs (IC50 values 15-18 microM) inhibit GTP-dependent vesicle fusion in rat liver microsomal vesicles. Acyl-CoAs of carbon chain length C8 and C20 are much less effective than acyl-CoAs of carbon chain length C14-C18. The effect of CoA is mimicked by dephospho-CoA,...

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Detalles Bibliográficos
Main Authors: Comerford, J G, Dawson, A P
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132205/
https://ncbi.nlm.nih.gov/pubmed/8380999
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