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Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production.

In human neutrophils, the chemotactic peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) induces increases in the intracellular free Ca2+ concentration ([Ca2+]i) with subsequent activation of beta-glucuronidase release and superoxide (O2-) production. Results from several laboratories sugg...

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Detaylı Bibliyografya
Asıl Yazarlar: Krautwurst, D, Seifert, R, Hescheler, J, Schultz, G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1992
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131990/
https://ncbi.nlm.nih.gov/pubmed/1281979
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