Tegument-Specific, Virus-Reactive CD4 T Cells Localize to the Cornea in Herpes Simplex Virus Interstitial Keratitis in Humans

Herpes stromal keratitis (HSK) is a prevalent and frequently vision-threatening disease associated with herpes simplex virus type 1 (HSV-1) infection. In mice, HSK progression occurs after viral clearance and requires T cells and neutrophils. One model implicates Th1-like CD4 T cells with cross-reac...

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Autori principali: Koelle, David M., Reymond, Sigrid N., Chen, Hongbo, Kwok, William W., McClurkan, Christopher, Gyaltsong, Tashi, Petersdorf, Effie W., Rotkis, Walter, Talley, Audrey R., Harrison, Devin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC113172/
https://ncbi.nlm.nih.gov/pubmed/11069987
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