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Alloxan inhibits ligand binding to adrenoceptors of vascular smooth muscle microsomes.

We have examined the effects of alloxan on the binding of [3H]prazosin and [125I]monoiodocyanopindolol (ICYP) to plasma-membrane-enriched microsomes isolated from dog aortas and dog mesenteric arteries respectively. Preincubation of the vascular smooth muscle membranes with alloxan reduced the numbe...

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Detalles Bibliográficos
Main Authors: Kwan, C Y, Sipos, S, Gaspar, V
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131689/
https://ncbi.nlm.nih.gov/pubmed/2396973
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