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Studies on the biotin-binding sites of avidin and streptavidin. Tyrosine residues are involved in the binding site.

The involvement of tyrosine in the biotin-binding sites of the egg-white glycoprotein avidin and the bacterial protein streptavidin was examined by using the tyrosine-specific reagent p-nitrobenzenesulphonyl fluoride (Nbs-F). Modification of an average of about 0.5 mol of tyrosine residue/mol of avi...

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Bibliographic Details
Main Authors: Gitlin, G, Bayer, E A, Wilchek, M
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131609/
https://ncbi.nlm.nih.gov/pubmed/2386489
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