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Identification of a new metalloproteinase inhibitor that forms tight-binding complexes with collagenase.

Connective-tissue cells produce a family of metalloproteinases which, once activated, can degrade all the components of the extracellular matrix. These potent enzymes are all inhibited by the tissue inhibitor of metalloproteinases (TIMP), and it was thought that the levels of this inhibitor controll...

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Detalhes bibliográficos
Main Authors: Cawston, T E, Curry, V A, Clark, I M, Hazleman, B L
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131549/
https://ncbi.nlm.nih.gov/pubmed/2165393
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