Proteolysis of the human DNA polymerase ɛ catalytic subunit by caspase-3 and calpain specifically during apoptosis
Human DNA polymerase epsilon (pol ɛ) normally contains a 261-kDa catalytic subunit (p261), but from some sources it is isolated as a 140-kDa catalytic core of p261. This shortened form possesses normal or somewhat enhanced polymerase activity and its significance is unknown. We report here that casp...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.21.4180 |
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