The CD11c antigen couples concanavalin A binding to generation of superoxide anion in human phagocytes.

We have found that an anti-CD11c monoclonal antibody (MAb) inhibits the respiratory burst induced in phorbol 12-myristate 13-acetate (PMA)-differentiated U937 cells as well as in human peripheral blood monocytes and neutrophils upon cell stimulation with concanavalin A. The MAb had no effect, howeve...

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Bibliografiske detaljer
Main Authors: Lacal, P M, Balsinde, J, Cabañas, C, Bernabeu, C, Sánchez-Madrid, F, Mollinedo, F
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131497/
https://ncbi.nlm.nih.gov/pubmed/1973035
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