Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP.

We directly manipulated the levels of PtdIns, PtdInsP and PtdInsP2 in digitonin-treated adrenal chromaffin cells with a bacterial phospholipase C (PLC) from Bacillus thuringiensis and by removal of ATP. The PtdIns-PLC acted intracellularly to cause a large decrease in [3H]inositol- or [32P]phosphate...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Eberhard, D A, Cooper, C L, Low, M G, Holz, R W
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131385/
https://ncbi.nlm.nih.gov/pubmed/2160809
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki