Biochemical characterisation of cap–poly(A) synergy in rabbit reticulocyte lysates: the eIF4G–PABP interaction increases the functional affinity of eIF4E for the capped mRNA 5′-end

The 5′ cap and 3′ poly(A) tail of eukaryotic mRNAs cooperate to synergistically stimulate translation initiation in vivo. We recently described mammalian cytoplasmic extracts which, following ultracentrifugation to partially deplete them of ribosomes and associated initiation factors, reproduce cap–...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Borman, Andrew M., Michel, Yanne M., Kean, Katherine M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113128/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.21.4068
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