Introduction of a cis-Acting Mutation in the Capsid-Coding Gene of Moloney Murine Leukemia Virus Extends Its Leukemogenic Properties

Inoculation of newborn mice with the retrovirus Moloney murine leukemia virus (MuLV) results in the exclusive development of T lymphomas with gross thymic enlargement. The T-cell leukemogenic property of Moloney MuLV has been mapped to the U3 enhancer region of the viral promoter. However, we now de...

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Bibliographic Details
Main Authors: Audit, Muriel, Déjardin, Jérôme, Hohl, Barbara, Sidobre, Christine, Hope, Thomas J., Mougel, Marylène, Sitbon, Marc
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC113102/
https://ncbi.nlm.nih.gov/pubmed/10559365
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