Evidence that a secondary binding and protecting site for factor VIII on von Willebrand factor is highly unlikely.

A binding domain for Factor VIII (F.VIII) has been previously identified on the N-terminal portion of human von Willebrand Factor (vWF) subunit [amino acids (AA) 1-272]. In order to characterize other possible structures of vWF involved in its capacity to bind and to protect F.VIII against human act...

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Main Authors: Layet, S, Girma, J P, Obert, B, Peynaud-Debayle, E, Bihoreau, N, Meyer, D
Formato: Artigo
Idioma:Inglês
Publicado: 1992
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130899/
https://ncbi.nlm.nih.gov/pubmed/1531749
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