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Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease.

Two synthetic peptides with sequences identical with those of fragments of the extracellular domain of the Alzheimer's-disease amyloid precursor protein (APP) were used to raise antibodies. SP28 comprises positions 597-624 of the APP695 isoform, whereas SP41 extends towards the N-terminus (amin...

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Detalles Bibliográficos
Main Authors: Ghiso, J, Wisniewski, T, Vidal, R, Rostagno, A, Frangione, B
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130811/
https://ncbi.nlm.nih.gov/pubmed/1372166
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