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Altering the Cellular Location of an Antigen Expressed by a DNA-Based Vaccine Modulates the Immune Response

The potential for DNA vaccines encoding mutated versions of the same antigen to modulate immune responses in C3H/HeN mice was investigated. We created expression plasmids that encoded several versions of glycoprotein D (gD) from bovine herpesvirus 1, including authentic membrane-anchored glycoprotei...

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Udgivet i:J Virol
Principais autores: Lewis, P. J., van Drunen Littel-van den Hurk, S., Babiuk, L. A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10214-10223.1999
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