Altering the Cellular Location of an Antigen Expressed by a DNA-Based Vaccine Modulates the Immune Response

The potential for DNA vaccines encoding mutated versions of the same antigen to modulate immune responses in C3H/HeN mice was investigated. We created expression plasmids that encoded several versions of glycoprotein D (gD) from bovine herpesvirus 1, including authentic membrane-anchored glycoprotei...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lewis, P. J., van Drunen Littel-van den Hurk, S., Babiuk, L. A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113075/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10214-10223.1999
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