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Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics.

Cytochrome P450s play a central role in the metabolism and disposition of an extremely wide range of drugs and chemical carcinogens. Individual differences in the expression of these enzymes may be an important determinant in susceptibility to adverse drug reactions, chemical toxins and mutagens. In...

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Autors principals: Forrester, L M, Henderson, C J, Glancey, M J, Back, D J, Park, B K, Ball, S E, Kitteringham, N R, McLaren, A W, Miles, J S, Skett, P
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130692/
https://ncbi.nlm.nih.gov/pubmed/1736885
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