Wild-Derived Inbred Mice Have a Novel Basis of Susceptibility to Polyomavirus-Induced Tumors

Polyomavirus induces a broad array of tumors when introduced into newborn mice of certain standard inbred strains, notably those bearing the H-2(k) haplotype. Susceptibility in these mice is conferred by an endogenous mouse mammary tumor virus superantigen (Mtv-7 sag) that acts to delete T cells req...

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Autors principals: Velupillai, Palanivel, Yoshizawa, Izumi, Dey, Dilip C., Nahill, Sharon R., Carroll, John P., Bronson, Roderick T., Benjamin, Thomas L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC113059/
https://ncbi.nlm.nih.gov/pubmed/10559322
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