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Activation of the PAK-Related Kinase by Human Immunodeficiency Virus Type 1 Nef in Primary Human Peripheral Blood Lymphocytes and Macrophages Leads to Phosphorylation of a PIX-p95 Complex

Human immunodeficiency virus type 1 (HIV-1) Nef enhances virus replication in both primary T lymphocytes and monocyte-derived macrophages. This enhancement phenotype has been linked to the ability of Nef to modulate the activity of cellular kinases. We find that despite the reported high-affinity in...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Brown, Amanda, Wang, Xia, Sawai, Earl, Cheng-Mayer, Cecilia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113039/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559302/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.9899-9907.1999
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