The Y-S-L-I Tyrosine-Based Motif in the Cytoplasmic Domain of the Human T-Cell Leukemia Virus Type 1 Envelope Is Essential for Cell-to-Cell Transmission

The human T-cell leukemia virus type 1 (HTLV-1) transmembrane glycoprotein has a 24-amino-acid cytoplasmic domain whose function in the viral life cycle is poorly understood. We introduced premature-stop mutations and 18 single-amino-acid substitutions into this domain and studied their effects on c...

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Bibliographic Details
Main Authors: Delamarre, Lélia, Pique, Claudine, Rosenberg, Arielle R., Blot, Vincent, Grange, Marie-Pierre, Le Blanc, Isabelle, Dokhélar, Marie-Christine
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC113006/
https://ncbi.nlm.nih.gov/pubmed/10516080
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