Mucosal but Not Parenteral Immunization with Purified Human Papillomavirus Type 16 Virus-Like Particles Induces Neutralizing Titers of Antibodies throughout the Estrous Cycle of Mice

We have recently shown that nasal immunization of anesthetized mice with human papillomavirus type 16 (HPV16) virus-like particles (VLPs) is highly effective at inducing both neutralizing immunoglobulin A (IgA) and IgG in genital secretions, while parenteral immunization induced only neutralizing Ig...

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Auteurs principaux: Nardelli-Haefliger, Denise, Roden, Richard, Balmelli, Carole, Potts, Alexandra, Schiller, John, De Grandi, Pierre
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112997/
https://ncbi.nlm.nih.gov/pubmed/10516071
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