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Requirements for RNA Replication of a Poliovirus Replicon by Coxsackievirus B3 RNA Polymerase

A chimeric poliovirus type 1 (PV1) genome was constructed in which the 3D RNA polymerase (3D(pol)) coding sequences were replaced with those from coxsackievirus B3 (CVB3). No infectious virus was produced from HeLa cells transfected with the chimeric RNA. Processing of the PV1 capsid protein precurs...

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Bibliographic Details
Main Authors: Bell, Yolanda C., Semler, Bert L., Ehrenfeld, Ellie
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112976/
https://ncbi.nlm.nih.gov/pubmed/10516050
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