Poliovirus Mutants at Histidine 195 of VP2 Do Not Cleave VP0 into VP2 and VP4

The final stage of poliovirus assembly is characterized by a cleavage of the capsid precursor protein VP0 into VP2 and VP4. This cleavage is thought to be autocatalytic and dependent on RNA encapsidation. Analysis of the poliovirus empty capsid structure has led to a mechanistic model for VP0 cleava...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hindiyeh, Musa, Li, Qi-Han, Basavappa, Ravi, Hogle, James M., Chow, Marie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Structure and Assembly
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112939/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10516013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.11.9072-9079.1999
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