A Cell Line-Based Neutralization Assay for Primary Human Immunodeficiency Virus Type 1 Isolates That Use either the CCR5 or the CXCR4 Coreceptor

We describe here a cell line-based assay for the evaluation of human immunodeficiency virus type 1 (HIV-1) neutralization. The assay is based on CEM.NKR cells, transfected to express the HIV-1 coreceptor CCR5 to supplement the endogenous expression of CD4 and the CXCR4 coreceptor. The resulting CEM....

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Trkola, Alexandra, Matthews, Jamie, Gordon, Cynthia, Ketas, Tom, Moore, John P.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1999
Fag:	Pathogenesis and Immunity
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10516002/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.11.8966-8974.1999
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