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Thromboxane A2 mediates lung vasoconstriction but not permeability after endotoxin.

The effect of dazoxiben, a selective thromboxane (Tx) synthetase inhibitor, on systemic and pulmonary hemodynamics, eicosanoids, and lung permeability was assessed in awake goats with lung lymph fistulae following infusion of Escherichia coli endotoxin (1 microgram/kg). Animals received endotoxin ei...

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Detalhes bibliográficos
Main Authors: Winn, R, Harlan, J, Nadir, B, Harker, L, Hildebrandt, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1129256/
https://ncbi.nlm.nih.gov/pubmed/6886010
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