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Role in nude mice of interferon and natural killer cells in inhibiting the tumorigenicity of human hepatocellular carcinoma cells infected with hepatitis B virus

The human hepatoma cell line, PLC/PRF/5, which is persistently infected with hepatitis B virus (HBV), has integrated HBV-DNA, secretes HBV surface antigen (HBsAg), and does not grow readily in congenitally athymic (nu/nu) mice. The present investigation was undertaken to ascertain whether the low tu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shouval, Daniel, Rager-Zisman, Bracha, Quan, Phuc, Shafritz, David A., Bloom, Barry R., Reid, Lola M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1129230/
https://ncbi.nlm.nih.gov/pubmed/6192149
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