Lymphotropic Virions Affect Chemokine Receptor-Mediated Neural Signaling and Apoptosis: Implications for Human Immunodeficiency Virus Type 1-Associated Dementia

Chemokine receptors pivotal for human immunodeficiency virus type 1 (HIV-1) infection in lymphocytes and macrophages (CCR3, CCR5, and CXCR4) are expressed on neural cells (microglia, astrocytes, and/or neurons). It is these cells which are damaged during progressive HIV-1 infection of the central ne...

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Main Authors: Zheng, Jialin, Ghorpade, Anuja, Niemann, Douglas, Cotter, Robin L., Thylin, Michael R., Epstein, Leon, Swartz, Jennifer M., Shepard, Robin B., Liu, Xiaojuan, Nukuna, Adeline, Gendelman, Howard E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC112843/
https://ncbi.nlm.nih.gov/pubmed/10482576
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