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Factors Affecting the Terminal Resolution Site Endonuclease, Helicase, and ATPase Activities of Adeno-Associated Virus Type 2 Rep Proteins

The Rep68 and Rep78 proteins (Rep68/78) of adeno-associated virus type 2 (AAV) are critical for AAV replication and site-specific integration. They bind specifically to the AAV inverted terminal repeats (ITRs) and possess ATPase, helicase, and strand-specific/site-specific endonuclease activities. I...

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Udgivet i:J Virol
Principais autores: Wu, Jianwen, Davis, Michael D., Owens, Roland A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112841/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482574/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8235-8244.1999
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