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CD40-Mediated Induction of CD4 and CXCR4 on B Lymphocytes Correlates with Restricted Susceptibility to Human Immunodeficiency Virus Type 1 Infection: Potential Role of B Lymphocytes as a Viral Reservoir

Human immunodeficiency virus type 1 (HIV-1) replicates primarily in lymphoid tissues where it has ready access to activated immune competent cells. We used one of the major pathways of immune activation, namely, CD40-CD40L interactions, to study the infectability of B lymphocytes isolated from perip...

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Autori principali: Moir, Susan, Lapointe, Réjean, Malaspina, Angela, Ostrowski, Mario, Cole, Charsey E., Chun, Tae-Wook, Adelsberger, Joseph, Baseler, Michael, Hwu, Patrick, Fauci, Anthony S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC112811/
https://ncbi.nlm.nih.gov/pubmed/10482544
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