Exposure to benzene and urinary concentrations of 8-hydroxydeoxyguanosine, a biological marker of oxidative damage to DNA.

OBJECTIVES--Benzene is an established animal and human carcinogen. The mechanism of benzene toxicity, particularly its leukaemogenic effect, is not fully understood. The modified base 8-hydroxy-deoxyguanosine (8-OHdG) is a sensitive marker of the DNA damage due to hydroxyl radical attack at the C8 o...

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Detalhes bibliográficos
Main Authors: Lagorio, S, Tagesson, C, Forastiere, F, Iavarone, I, Axelson, O, Carere, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1128097/
https://ncbi.nlm.nih.gov/pubmed/7849850
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