STAT6-Deficient Mice Exhibit Normal Induction of Murine AIDS and Expression of Immunoglobulin E following Infection with LP-BM5 Murine Leukemia Viruses

The unique Gag polyprotein of the replication-defective virus responsible for murine AIDS (MAIDS) induces B-cell activation, proliferation, and differentiation, including immunoglobulin class switch-recombination to immunoglobulin E (IgE). Secretion of IgE normally requires the serial induction of i...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Morse, Herbert C., McCarty, Thomas, Giese, Nathalia A., Taddesse-Heath, Lekidelu, Grusby, Michael J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.7093-7095.1999
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