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Evolution of the Hepatitis C Virus Second Envelope Protein Hypervariable Region in Chronically Infected Patients Receiving Alpha Interferon Therapy

Sustained hepatitis C virus (HCV) RNA clearance is achieved in 8 to 12% of patients with chronic HCV infection treated with alpha interferon (IFN-α) at the approved dose of 3 MU three times a week for 6 months and in about 25% of those receiving this treatment for 12 months. We used single-strand co...

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Autors principals: Pawlotsky, Jean-Michel, Germanidis, Georgios, Frainais, Pierre-Olivier, Bouvier, Magali, Soulier, Alexandre, Pellerin, Muriel, Dhumeaux, Daniel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC112731/
https://ncbi.nlm.nih.gov/pubmed/10400744
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