The Furin Protease Cleavage Recognition Sequence of Sindbis Virus PE2 Can Mediate Virion Attachment to Cell Surface Heparan Sulfate

Cell culture-adapted Sindbis virus strains attach to heparan sulfate (HS) receptors during infection of cultured cells (W. B. Klimstra, K. D. Ryman, and R. E. Johnston, J. Virol. 72:7357–7366, 1998). At least three E2 glycoprotein mutations (E2 Arg 1, E2 Lys 70, and E2 Arg 114) can independently con...

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Bibliographic Details
Main Authors: Klimstra, William B., Heidner, Hans W., Johnston, Robert E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112708/
https://ncbi.nlm.nih.gov/pubmed/10400721
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