Comparative Fitness of Multi-Dideoxynucleoside-Resistant Human Immunodeficiency Virus Type 1 (HIV-1) in an In Vitro Competitive HIV-1 Replication Assay

We examined whether human immunodeficiency virus type 1 (HIV-1) fitness was altered upon the acquisition of a set or subset of five mutations (A62V, V75I, F77L, F116Y, and Q151M) in the pol gene, which confers resistance to multiple dideoxynucleosides (MDR), as well as the zidovudine resistance-asso...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Kosalaraksa, Pope, Kavlick, Mark F., Maroun, Victor, Le, Richard, Mitsuya, Hiroaki
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1999
Subjects:	Vaccines and Antiviral Agents
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112591/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364282/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5356-5363.1999
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