Intracisternal Type A Particle-Mediated Activation of the Notch4/int3 Gene in a Mouse Mammary Tumor: Generation of Truncated Notch4/int3 mRNAs by Retroviral Splicing Events

The int3 oncogene was discovered as a frequent target in mouse mammary tumor virus-induced mammary tumors and encodes the intracellular domain of a Notch4/int3 protein. In one spontaneous mammary tumor, no. 9, that developed in a BALB/c mouse, we have found an insertion of a 1.2-kb sequence, consist...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Jong-Seo, Haruna, Tatsuya, Ishimoto, Akinori, Honjo, Tasuku, Yanagawa, Shin-ichi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
Ämnen:
Transformation and Oncogenesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC112564/
https://ncbi.nlm.nih.gov/pubmed/10233982
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