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Natural Variation in Translational Activities of the 5′ Nontranslated RNAs of Hepatitis C Virus Genotypes 1a and 1b: Evidence for a Long-Range RNA-RNA Interaction outside of the Internal Ribosomal Entry Site

The 5′ nontranslated RNA (5′NTR) of a genotype 1b hepatitis C virus (HCV-N) directs cap-independent translation of the HCV-N polyprotein with about twofold less efficiency than the 5′NTR of a genotype 1a virus under physiologic conditions (Hutchinson strain, or HCV-H) (M. Honda et al., Virology 222:...

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Udgivet i:J Virol
Principais autores: Honda, Masao, Rijnbrand, Rene, Abell, Geoff, Kim, Desok, Lemon, Stanley M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112538/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10233956/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.6.4941-4951.1999
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