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Correct Integration of Model Substrates by Ty1 Integrase

The retrovirus-like mobile genetic element of Saccharomyces cerevisiae, Ty1, transposes to new genomic locations via the element-encoded integrase (IN). Here we report that purified recombinant IN catalyzed correct integration of a linear DNA into a supercoiled target plasmid. Ty1 virus-like particl...

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Detalles Bibliográficos
Main Authors: Moore, Sharon P., Garfinkel, David J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC112432/
https://ncbi.nlm.nih.gov/pubmed/11090149
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