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Intracellular Hepatitis B Virus Nucleocapsids Survive Cytotoxic T-Lymphocyte-Induced Apoptosis

Following antigen recognition, hepatitis B virus (HBV)-specific cytotoxic T lymphocytes (CTL) induce a necroinflammatory liver disease in HBV-transgenic mice. An early event in this process is CTL-dependent activation of apoptosis in a small fraction of HBV-positive hepatocytes. Here we show that cy...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Pasquetto, Valerie, Wieland, Stefan, Chisari, Francis V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112416/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11000256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.20.9792-9796.2000
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