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Alphavirus RNA Genome Repair and Evolution: Molecular Characterization of Infectious Sindbis Virus Isolates Lacking a Known Conserved Motif at the 3′ End of the Genome

The 3′ nontranslated region of the genomes of Sindbis virus (SIN) and other alphaviruses carries several repeat sequence elements (RSEs) as well as a 19-nucleotide (nt) conserved sequence element (3′CSE). The 3′CSE and the adjoining poly(A) tail of the SIN genome are thought to act as viral promoter...

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Bibliographic Details
Main Authors: George, Jyothi, Raju, Ramaswamy
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112414/
https://ncbi.nlm.nih.gov/pubmed/11000254
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