Roles of the AX(4)GKS and Arginine-Rich Motifs of Hepatitis C Virus RNA Helicase in ATP- and Viral RNA-Binding Activity

The nonstructural protein 3 (NS3) of hepatitis C virus (HCV) possesses protease, nucleoside triphosphatase, and helicase activities. Although the enzymatic activities have been extensively studied, the ATP- and RNA-binding domains of the NS3 helicase are not well-characterized. In this study, NS3 pr...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Chang, Shin C., Cheng, Ju-Chien, Kou, Yi-Hen, Kao, Chuan-Hong, Chiu, Chiung-Hui, Wu, Hung-Yi, Chang, Ming-Fu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112406/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11000246/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.20.9732-9737.2000
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