Comparison of Second-Strand Transfer Requirements and RNase H Cleavages Catalyzed by Human Immunodeficiency Virus Type 1 Reverse Transcriptase (RT) and E478Q RT

Truncated tRNA-DNA mimics were examined in an in vitro assay for second-strand transfer during human immunodeficiency virus type 1 (HIV-1) reverse transcription. Strand transfer in this system requires the progressive degradation of the RNA within the 18-mer tRNA-DNA (plus-strand strong stop DNA) in...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Snyder, Christine Smith, Roth, Monica J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112399/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11000239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.20.9668-9679.2000
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