The Murine Double-Stranded RNA-Dependent Protein Kinase PKR Is Required for Resistance to Vesicular Stomatitis Virus

Interferon (IFN)-induced antiviral responses are mediated through a variety of proteins, including the double-stranded RNA-dependent protein kinase PKR. Here we show that fibroblasts derived from PKR(−/−) mice are more permissive for vesicular stomatitis virus (VSV) infection than are wild-type fibr...

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Main Authors: Stojdl, David F., Abraham, Ninan, Knowles, Shane, Marius, Ricardo, Brasey, Ann, Lichty, Brian D., Brown, Earl G., Sonenberg, Nahum, Bell, John C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC112389/
https://ncbi.nlm.nih.gov/pubmed/11000229
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