A TVA–Single-Chain Antibody Fusion Protein Mediates Specific Targeting of a Subgroup A Avian Leukosis Virus Vector to Cells Expressing a Tumor-Specific Form of Epidermal Growth Factor Receptor

We have previously described an approach that employs retroviral receptor-ligand bridge proteins to target retroviral vectors to specific cell types. To determine whether targeted retroviral entry can also be achieved using a retroviral receptor–single-chain antibody bridge protein, the TVA-MR1 fusi...

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Main Authors: Snitkovsky, Sophie, Niederman, Thomas M. J., Carter, Bob S., Mulligan, Richard C., Young, John A. T.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
主題:
Gene Therapy
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC112384/
https://ncbi.nlm.nih.gov/pubmed/11000224
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