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Sequence Variability of Borna Disease Virus: Resistance to Superinfection May Contribute to High Genome Stability in Persistently Infected Cells

The RNA genome of Borna disease virus (BDV) shows extraordinary stability in persistently infected cell cultures. We performed bottleneck experiments in which virus populations from single infected cells were allowed to spread through cultures of uninfected cells and in which RNase protection assays...

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Main Authors: Formella, Stephan, Jehle, Christian, Sauder, Christian, Staeheli, Peter, Schwemmle, Martin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC112318/
https://ncbi.nlm.nih.gov/pubmed/10933695
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