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Vaccine Protection against Simian Immunodeficiency Virus by Recombinant Strains of Herpes Simplex Virus

An effective vaccine for AIDS may require development of novel vectors capable of eliciting long-lasting immune responses. Here we report the development and use of replication-competent and replication-defective strains of recombinant herpes simplex virus (HSV) that express envelope and Nef antigen...

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Detalhes bibliográficos
Main Authors: Murphy, Cynthia G., Lucas, William T., Means, Robert E., Czajak, Susan, Hale, Corrina L., Lifson, Jeffrey D., Kaur, Amitinder, Johnson, R. Paul, Knipe, David M., Desrosiers, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112303/
https://ncbi.nlm.nih.gov/pubmed/10933680
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