Increased Neutralization Sensitivity and Reduced Replicative Capacity of Human Immunodeficiency Virus Type 1 after Short-Term In Vivo or In Vitro Passage through Chimpanzees

Development of disease is extremely rare in chimpanzees when inoculated with either T-cell-line-adapted neutralization-sensitive or primary human immunodeficiency virus type 1 (HIV-1), at first excluding a role for HIV-1 neutralization sensitivity in the clinical course of infection. Interestingly,...

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Main Authors: Beaumont, Tim, Broersen, Silvia, van Nuenen, Ad, Huisman, Han G., de Roda Husman, Ana-Maria, Heeney, Jonathan L., Schuitemaker, Hanneke
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC112298/
https://ncbi.nlm.nih.gov/pubmed/10933675
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